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PI3K–AKT and Cellular Metabolism

PI3K–AKT signaling acts as an important interface between extracellular signals and intracellular metabolism.

AKT can regulate processes associated with:

  • Glucose utilization
  • Glycogen metabolism
  • Lipid metabolism
  • Protein synthesis
  • Energy balance

This makes PI3K–AKT an important pathway for understanding how cells coordinate growth with nutrient availability.